Analysis was made on the diamond positioning arrangement mode and parameters of impregnated diamond bit, 40/45 mesh and 50/60 mesh diamond positioning arrangement drill bits were designed and produced. In the drilling experiments of Mengcun mining area in Guangxi, the service life of 40/45 mesh diamond bit is respectively 1.84 times of conventional bit; the service life of 50/60 mesh diamond bit is respectively 2.74 times of conventional bit, and the drilling rate increased by 19.7%.