Xinzhou tunnel section of Datong-Xi’an is oblique crossing Dayun expressway, the tunnel top is near the collapsible soil of expressway, so settlement control requirements are very strict. By one-time advanced support using self drilling pipe shed, the safe operation of expressway was ensured and pavement settlement was effectively controlled. The construction practice shows that self drilling pipe shed has advantages of one-time long distance construction, precious construability, less ground settlement and controllable grouting fullness, and can be the reference to the application of self drilling pipe shed technology.