This paper introduces a design plan of the combined reinforcement of high slope deformation based on pre-stressed anchor cable and the cantilever pile (wall). By the supplementary investigations of the slope geological lithology and the stress analysis on the internal force of slope protection pile structure, the causes of the high slope deformation and the local cracks of the pile were found out; the reinforced cantilever pile (wall) was designed with pre-stressed anchor cable for use. After a long time monitoring, the maximum displacement of pile head is accumulative 30.1mm in 3 years, which is less than the national regulations. It shows that the design of pile-anchor reinforcement if safe and reliable and the successful experience can be reference for the similar project.