The rescue of Pingyi mine disaster in Dec25. 2015 is the first successful rescue case by hole drilling in China. The continuous collapse and deformation result in complicated stratum conditions, which caused much difficulty to the rescue drilling hole construction. As to these special conditions, air reverse circulation drilling technology was used; and airlift reverse circulation drilling technology was used to deal with drilling accidents. This paper summarizes the experience of large diameter drilling construction and puts forward some problems to be improved in the future.