As the development trend, drilling engineering will become intelligent, automated and IT based. In order to obtain safe, accurate and efficient real-time data at the drilling site, an wireless real-time transmission system for deep-hole intelligent drilling parameters, which combines three wireless transmission modes was researched. With modular programming based on the LabVIEW software platform, the wireless real-time transmission system composed of five major modules was developed, including a wireless transmission and reception module, a remote network transmission module, a database module, a complex drilling condition recognition module and an accident diagnosis module. Indoor simulation tests and field application showed that it meets the requirements of field application, and can be applied to complex, deep-hole, and intelligent drilling sites, which may meet the needs of deep resource exploration engineering, and provide support for national important energy resource exploration projects.