In the past 63 years since the establishment of Bureau of Geology and Mineral Exploration and Development of Guizhou Province， drilling engineering as an important means of geological prospecting has developed into a professional system with complete categories，sophisticated equipment and exquisite technology. On the basis of summarizing the brilliant achievements in geological prospecting of Bureau of Geology and Mineral Exploration and Development of Guizhou Province，this paper reviews in detail the development process of drilling engineering in several key directions，such as small diameter core drilling， large-diameter deep well drilling， mechanized water well drilling，shallow geothermal drilling， etc.； presents a prospect on the future development trend； and puts forward relevant suggestions as reference for future work.