Based on the 1∶50000 scale hydrogeological survey carried out in the bedrock area of the low mountains and hills in the central and southern part of Shandong province， the hydrogeological characteristics are analyzed by means of hydrogeological survey， hydrogeological drilling， geophysical exploration， pumping test， water quality analysis and other technical methods. The results show that the groundwater types in the area can be divided into four types： loose rock pore water， clastic rock pore fissure water， carbonate rock fissure karst water and bedrock fissure water. The groundwater recharge， runoff， discharge conditions and their evolution as well as environmental hydrogeology are also analyzed. Three quaternary pore water rich zones with the capacity of centralized water supply are delineated， and two types of bedrock water storage structures：the stratigraphic water-retaining structure and the fault water-storage structure， are summarized. Groundwater quality is dominated with Class Ⅲ， Ⅳ and Ⅴ， and the components higher than the Class Ⅲ standard include mainly nitrate， total hardness， iron， followed by fluoride， etc. With the water prospecting model developed for the area， a total of 10 hydrogeological boreholes with water supply capacity were constructed， with a total water yield of 7017.84m³/d， which can meet portable water supply for nearly 100，000 people and irrigation for more than 5900 mu farmland. The results can be used as guide for exploring new target aquifers for water supply and to locating water wells.