The Jiama 3000m Scientific Drilling Project in Tibet is the first 3000m scientific drilling project in the field of solid mineral investigation in the Qinghai-Tibet Plateau， and its purpose is to predict deep mineral resources directly， build a comprehensive exploration model with multiple information， and realize the demonstration of increasing reserves through the study of fine anatomy of orebody structures， hyperspectral analysis and mineral exploration indicators. This paper introduces the general drilling operations and key technologies in 3000m scientific deep drilling in Jiama， Tibet. With use of HXY-8VB type frequency conversion manual-automatic drilling rig， eccentric deviation correction drill bits， automatic vertical drilling tools， “drilling and reaming” drill bits， environmental protection flushing fluid systems and other technological measures， many technical difficulties， including selection of drilling equipment， deep hole trajectory control， complex formation coring， green exploration， have been solved. The project is completed at final hole depth of 3003.33m， creating the record in small-diameter solid ore exploration depth in the Qinghai-Tibet Plateau. It not only provides detailed physical data for the study of deep-hole mineral metallogenic theory and resource exploration in this area， but also provides technical reference for extra-deep hole drilling on the plateau.