In order to ensure well control safety, existing plugging materials have been added to the drilled areas of Changqing Oilfield for common leakage. However, there are technical difficulties such as water hole blockage of drilling tools, lack of signal from downhole instruments, and low success rate of one-time plugging. Therefore, wireless drilling instruments and downhole power tools have been optimized, and matching drilling plugging slurry has been developed to achieve rapid plugging of the leaking layer while meeting the requirements of permeability. This has formed the Changqing area drilling plugging technology, which has been applied in more than 100 wells on site, increasing the success rate of one-time plugging by 23.54%, significantly shortening the plugging time, improving plugging efficiency, and ensuring safe and rapid drilling and completion of wells.