Combined with the Guomao Subway Station on Beijing metro line 10, by means of ABAQUS software, construction process and construction effect on adjacent 19-3 pile foundation of Guomao Bridge are simulated and the deformation and force character of pile foundation as well as the interaction mechanism of pile-soil are studied. The partial results acquired by simulation and measure are consistent by compare and a mass of harvest is achieved. The conclusions are reached that 19-3 pile foundation of Guomao Bridge is safe during construction and existing construction project is reliable. The basis and guidance are provided for succedent Guomao Metro Station and similar engineering construction.