According to the characteristics of cofferdam, control of grouting with static pressure casing was used for wall protection of borehole construction in unconsolidated formation and filled foundation to increase efficiency of borehole completion. Combined with casing location, grouting pressure and slurry ratio were adjusted to control the diffusion radius of grouting slurry and control the grouting location and grouting effect. The paper also introduced the application of control of grouting method with static pressure casing in anti-seepage for cofferdam of Dongqing hydropower station in Guizhou.