The left resistance block of Jinping I hydropower station on Yalong River was built on f2、f5、f8、f42-9 faults and the weak belt with lamprophyre vein and deep fractures, reinforcement treatment was necessary. Chemical compound grouting was developed based on cement grouting, the test was introduced in selection of chemical grouting material, determination of grouting parameters and grouting construction technology. Based on the test result, analysis was made on grouting feasibility in lamprophyre vein and testing evaluation was made on grouting effect by the comparative analysis on core, permeability of surrounding rocks, rock acoustic wave and deformation modulus in borehole, it showed that chemical compound grouting has obvious effect on reinforcement treatment in lamprophyre vein. The paper also gives the construction suggestion according to the grouting test.