In this article, the effects of different drilling technical parameters on drilling efficiency are discussed and it had been suggested that the aim for optimized configuration of drilling equipment is to obtain the optimized drilling technical parameters and then the optimized drilling efficiency. The main elements of drilling equipment including drill rig, drilling method, WL coring drill rod, coring bit, directional drilling tools and mud pump are analyzed and the suggestions on the optimization of the elements are made. On the basis of elementary analysis, a proposal on the optimized configuration of deep exploration core drilling equipment is put forward.