The well Niure 4 is located in Niutuo Town, Gu’an County of Hebei Province. The well drilling construction was carried in the Eugene and drilled to the gypsum mudstone stratum with the thickness of 300m. Through strengthening management of drilling fluid quality, the drilling fluid performance was adjusted by ferric chromic salt, CMC, sulfonated asphalt, polyacrylic acid potassium and alkali; water-swellable collapsing in mudstone stratum was successfully resolved.