Because of high demand on the horizontal displacement and vertical precision in inversion construction of steel pipe column, it is difficult to meet design requirement by general support stud construction method; and the concrete with different marks for pile body and the lining inside of steel pipe in the structure design bring challenge in grouting quality. With an engineering case of Wuhan, the paper introduced inversion construction of steel pipe column in steel pipe column location, verticality control and grouting of different concretes.