Based on the analysis on the advantages and disadvantages of bored grouting pile, pre-stressed concrete pipe pile and pre-cast reinforced concrete square pile common used in east China at present, a technology of the combination of pile-end post-grouting and pre-cast reinforced concrete square pile was put forward. It was verified by project cases that this technology could increase the bearing capacity of single pile with low cost and also could remedy defects of high noise, low efficiency and environmental pollution in the construction of the bored grouting pile. The paper introduced the design and the construction process of this combined technology.