Aimed at the wall protection difficulties in multiple interlayer and karst stratum, which can not be solved by traditional wall protection means, high pressure jet grouting cement slurry technology was put forward and successfully developed. By the practice experiences in several mining areas and boreholes, the reliable and effective “cement casing” has formed by wall protection technology with high pressure jet grouting cement slurry in collapse and oversized hole sections in any depth and loose strata. The paper systematically introduces this technology about its process principle, the technical points, the application and popularization.