In long distance tunneling with large diameter air cushion slurry balance shield machine under different geological conditions, different degrees of wear on shield machine cutter will be produced; especially in sand and gravel based formation, the formation with excessive level of quartz and soft & hard formation, the cutter head and cutter are more easy to be worn. In order to ensure the safe use of shield machine cutter head, inspection and replacement of edge cutter and center cutter often should be done according to the different wear standards in the cabin with pressure. With an engineering case of cutter inspection/replacement in cabin with pressure for river channel construction, the paper summed up the construction technology of cutter inspection/replacement in cabin with pressure for large diameter shield.