Based on an excavation retaining project in Beijing, the paper describes the application of pile-anchor retaining structure in excavation retaining and the deformation control from the design point of view. According to the stress features and structure characteristics, main reinforcement of slope protection pile is unevenly arranged and segment reinforcement is adopted. Concrete middle beam was added in the middle of brick wall to ensure the excavation safety. In the slope protection pile construction, different construction technologies were used to protect the old trees in the slope protection range. From the excavation point view, horizontal displacement on top of retaining structure and subsidence of surrounding building structures were monitored, and the anchor was tested and monitored. The analysis shows that the horizontal and vertical deformation of excavation are in the scope of designed control range, the foundation pit is of overall stability, the pile-anchor retaining structure has played an effective control effect on the deformation.