With an engineering case of side slope sliding protective control for K2542 750～810 in Guilin-Yangshuo expressway, the paper introduces the application of the combination of anchoring-drawing anti-slide pile and anchor spray technology for rapid sliding landslide protective strengthening. The landslide is mainly composed of rocks and soil of fault fracture zone with complex geological structure, rock breaking, large rock pores, rich groundwater in rainy season, complex composition of slope rocks and large difference in mechanical properties; what was more, it was in the rapid sliding stage, this technical methods and some comprehensive measures were taken in the engineering design and the construction with good effects.