The formation process of lunar regolith and the material composition are introduced, by the comparison of basic physical and mechanical indexes of lunar regolith with stimulated CUG-1 lunar regolith and common dry sand, it is indicated that in the lunar sample drilling process, hard aggregate (briquettes) with certain cementing strength may be encountered. The core task of the third stage lunar exploration project of China is to realize lunar drilling and sampling as well as returning, and obtain lunar regolith samples in deep layer with original bedding structure. Because of the extreme environment of lunar surface, the structure of coring tools should be simple to reduce accident rate with broaden adaptability to regolith layer drilling. With the stimulated lunar regolith, the experimental research is respectively made on traditional borehole drilling, downhole coring tool, lunar surface sampling tool, soft bag overturning coring tool and double-tube (inner and outer tubes) coring tool, it shows the combined coring tool with inner and outer tubes can meet the requirements of China’s lunar sample drilling and returning.