This article describes a case of deep foundation pit construction for Huangpulu sewage treatment plant, which was by Yangtze River with complex geological conditions. The paper points out the harm of groundwater in the construction of deep foundation pit and discusses the methods and the major points of treatment. Dewatering is inevitable in the process of deep foundation water treatment but peripheral settlement can be avoided. With reasonable treatment scheme, ensured well quality and standard-operation, the construction requirements on dry operation can be reached.