Based on geological survey, salt well technical parameters and requirements, drilling equipments, drilling technology and other aspects in the brine well in Guyuan of Ningxia, this paper introduces the brine well construction, focuses on the key technical measures of drilling fluid, cementing and butt construction, etc. and lists the outstanding issues appeared in the construction, such as clay mixing into drilling fluid, gypsum-containing shale necking collapse and sand setting in high angle wells segment, the processing methods are analyzed and the experiences and lessons of brine well construction are summarized.