According to the particularity and severity of environmental protection situation for the nuclear geological prospecting industry, it is necessary to construct a safe production management system suitable for the geological prospecting units. Based on “nuclear” character, this system should be focused on the safety management of radiation source protection, radiation protection and environmental protection, use modern scientific and technological means to increase the safety assurance coefficient and promote closed-loop management level of hidden danger in field operation under the conditions with no technical and logistic support; carry forward the safety culture idea and improve the safety culture system with the characteristics of nuclear geological prospecting to make the safety management in the nuclear geological prospecting from the traditional experience management to the modern scientific management. With scientific management methods, the security risks in the production process can be controlled in the minimum range to ensure the sustainable development of nuclear geological prospecting industry.