Before the operation of shale gas production well, large-scale should be carried out, the production casing must be able to bear the construction pressure of ≥90MPa. In 2013, unsteady pressure happened in 2 wells of testing well group in Fuling working area, which resulted in the subsection fracturing technology being confined in long horizontal for reservoir reconstruction, this problem sometimes became the bottleneck that resticted Fuling shale gas drilling production and quality. Therefore, the technical measures of leakage proof and plugging were studied in production casing design, construction and treatment with some progress to meet the requirement of efficient shale gas development. This paper introduces the countermeasures and practice achievements in leakage proof and plugging of casing in the first phase of Fuling shale gas, whi