Various types of lost circulation occured frequently in Fuling shale gas well drilling, which seriously impacted the engineering quality, especially the oil-based drilling fluid leakage happened in the third segment of long horizontal section and even in cementation stage, both cementation quality and late shale gas exploitation were affected. In view of the characteristics of absorption well, a series of borehole preparation techniques, high performance fiber, spacer fluid plugging, optimal outside pipe slurry column structure, wall stability under pressure for absorption well cementation were studied to improve plugging performance and cementation quality. With enlargement of the exploitation area, the geological conditions will be more complicated, the paper puts forward the further research direction and the suggestion.