Based on the introduction of common stratum of non metallic mineral exploration, boring characteristics and wire-line core drilling, the causes of accidents such as sticking and pump suffocation are analyzed with the countermeasures. This paper summarizes the wire-line core drilling experience about flushing fluid types, performance requirements and maintenance management in soft and loose strata; emphatically presents SJP cement slurry and its application in grouting technology for borehole plugging.