High pressure jet grouting as a grouting form born of the hydraulic coal mining and static pressure grouting combination has been successfully applied to geo-hazard prevention, reservoir dam and landfill leachate seepage prevention and reinforcement engineering, and achieved remarkable economic and social benefits. This paper discusses high pressure jet grouting seepage prevention and reinforcement from six aspects, including characteristics of high pressure jet flow, mechanism of high pressure jet grouting, factors influencing the formation of anti seepage consolidation body by high pressure jet grouting and its imperviousness, factors influencing the cutting and mixing range of high pressure jet grouting in formations, requirements of high pressure jet grouting on grouting materials, and common accidents and countermeasures of high pressure jet grouting. It has been put forward that the application of new technologies such as SJP grouting material and bionic non-smooth technology to high pressure jet grouting for resolving existing problems is a meaningful attempt and is also feasible.