The formations are mainly of steep occurrence of phyllite in Tiziya-Fuziling lead-zinc polymetallic ore area, locally containing calcite or quartz veins with fault fracture zone development and poor wall stability, the design requirements could not be met because of common severe drilling hole bending. The hole deviation prevention, deviation correction and slurry protection are the major construction technical problems in this mining area. This paper introduces the technical measures taken in hole deviation prevention, directional deflection, wall protection and plugging, as well as the results achieved.