Based on the introduction of drilled strata characteristics of Zhuxi mining area, the construction difficulties are analyzed systematically in the aspects of deep drilling depth and easily being inclined, more complex formation comparing with shallow drilling, higher requirements of drilling quality, especially for hole inclining and some others. This paper summarizes the main drilling equipments selection, drilling construction management works and major technologies including drilling methods, hole structures, drill bit selection, drilling technical parameters, flushing fluid selection and hole wall protection and plugging measures; suggests improving construction capability of drilling equipments, curbing serious downhole accidents in future deep hole construction, insisting on the control principle of prevention first and treatment secondary and being prepared for hole wall protection with mud.