For deep hole drilling in complex formation, failure of inner tube drilling tools fishing, failure of core breaking, core erosion and so on are easy to happen in using wire-line coring drilling technology. Combined with the development status of wire-line coring tool both in China and abroad and starting from the practical problems, the optimum design thoughts of drilling tool structure are given including coating drag reduction and vibratory plugging removal of core barrel, anti-jacking design of latch mechanism, friction increase between core lifter and core, increase of the flowing area inside the drilling tool, change of the flushing fluid flowing direction near the bit and so on in this paper in order to further improve the drilling efficiency of the wire-line coring tool in deep hole drilling.