During the construction of solid core drilling in coalbed methane exploration well, when encountering the tectonic development of rock strata and developed underground water system, multi-layer leakage and difficult wall protection often happen. Because of the special requirements for logging operation in coalbed methane exploration wells, the wall protection and plugging become the key of drilling construction. In the process of wall protecting and plugging treatment, some improper technical methods and incorrect calculation can lead to the failure, even cause major drilling accident. By the summary of the construction experience of the work area, the feasible technical measures of wall protection and plugging are put forward, which provide reference for the similar stratum drilling exploration and construction.