In order to verify the difference between the round-hole screen pipe and the slotted screen pipe in the gas drainage process, this paper analyzes the passing performance of the conventional round-hole screen pipes and the slotted screen pipes with PFC3D discrete element analysis software. According to the simulation results, the slotting parameters are optimized, the gas drainage tests of the round-hole screen pipe and 3 kinds of the slotted screen pipe with different slotting parameters were carried out in coal seam 15# of 15117 working face in Yangquan mining area. The results of numerical simulation show that the volume of passed particles through the slotted screen pipes is less than that through the round-hole screen pipes; and for slotted screens, the effect of the slotted width on the volume of passed particles is greater than the slotted length. The field test shows that the average gas flow and gas concentration of the slotted screen pipe are 6 times and 3.8 times that of the round-hole screen pipe respectively, it proves that the smaller the volume of passed particles is, the better the anti-clogging performance is, and the better the gas drainage effect is.