The ore bodies of Jinping Chang’an Gold Mine exist in sandstone in the form of sulphide deposits, which has the characteristics of deep burial, steep dip and difficult exploration. In the design of exploration boreholes in the mining area, the azimuth ranges from 70° to 250°, the inclination from 30° to 75°, and the borehole depth from about 100m to 800m. In view of the complex situation of hard, broken and leaking formation, and with the large designed inclination and strict requirement on hole deviation in this mining area, a new type of drilling equipment (XDJ4 full hydraulic core drilling rig) was adopted for drilling with flushing fluid of low viscosity, low specific gravity and good lubricity for borehole wall protection. Control and correction of borehole deviation were carried out by taking measures such as control of drilling rig installation, deceleration method, small diameter pilot drilling followed with correction of deviation by increase of WOB. As a result, the construction difficulties such as easy deviation and leakage were effectively solved, and the project was completed with high quality and full quantity as well as on schedule, achieving good economic and social benefits. This paper summarizes some experience and existing problems in the construction of large inclination boreholes in this mining area, which provides good reference for the construction of similar projects.