Sand entry and well clogging in the groundwater heat pump system often affect the operation and efficiency of the system. Taking a project in Jingzhou City as an example, analysis is made of selection of the water well drilling method in gravel with fine sand aquifer occurring widely in Jianghan Plain and the problems with pack material and the screen design. It is pointed out that one of the effective means to prevent sand entry from the fine sand layer is to wrap the stainless steel wire mesh around the screen pipe at present; anyhow it’s better to be used in conjunction with the reverse circulation drilling method, and the pack material should be selected according to the gradation curve of the aquifer to avoid the transfer of the filtration pressure to the screen pipe, thus reducing well clogging.