The high temperature and high pressure composite insulation tubes are mainly used to solve the problem of borehole measurement under the condition of ultra-high temperature and ultra-high pressure. In order to obtain the key technologies such as vacuum heat insulation and high pressure seal in ultra-high temperature and ultra-high pressure environment, the high temperature and high pressure compound insulation tube being developed can provide a high temperature pressure-bearing tube for the ultra-high temperature borehole measuring instrument, which can be used at the temperature of 270℃ and pressure of 120MPa. The indoor test and field application show that the compound insulation tube can meet the requirements of ultra-high temperature and ultra-high pressure, can be applied in high temperature geothermal energy drilling engineering, hot dry rock drilling, scientific drilling project, deep mineral resources exploration and deep oil & gas resources exploration, which provides technical support for ultra-high temperature and deep drilling measurement.