In order to prevent the support crushing disaster, a technique is presented for pressure relieve blasting of concentrated coal pillars with the super long upward hole through analysis of the theory of disaster prevention by pressure relief and loosening blasting with super long upward holes. Three technical difficulties have been solved through field practices and some experiments. First, an explosive charging device was developed by ourselves for quick explosive charging even to 110m hole depth with the angle to 30°. Second, the optimal spacing of blasting holes was found through theoretical calculation. Third, the explosive safety detonation and elimination of plugging of the super long upward hole was achieved through the explosive test and the cement-silicate grouting’s setting properties test. Successful field blasting practices proved the technique can provide engineering reference and be promoted.