The Chuzhou salt-cavern gas storage facilities is supporting gas storage for Sino Russian East Line; thus, it is of great construction significance. During the drilling operation in the Chuzhou area, the upper Dongtai and Yancheng formations are prone to leak, and the clay is prone to make slurry. The salt formations in the lower Pukou formation are prone to erode, expand and collapse. Drilling fluid technology for different well sections was used according to stratum characteristics and construction difficulties in the Chuzhou area. The polymer drilling fluid was used to prevent surface leakage and collapse in the first well section. The salt water polymer drilling fluid was used to prevent shrinkage and gypsum invasion in the upper part of the second section and the saturated brine polymer drilling fluid was used to prevent salt dissolving in the salt layer section. The above drilling fluid technology has been verified by 3 wells in the field. The drilling process of the 3 wells was smooth, the well diameter was regular, no downhole complications occurred, the quality of the well was high, and the coring rate of the salt layer was above 99%. The drilling fluid technology can provide good guidance for drilling of gas storage wells.