In-situ leaching drilling is a kind of drilling for the mining purpose, where increase in the borehole water yield means increase in the borehole mining volume. Analysis of in-situ leaching drilling experience over many years and its theory found the main factors influencing the borehole water yield were the composition and properties of drilling mud, and permeability difference of artificial filtering layers. Therefore, three technical measures are proposed for in situ leaching drilling: vegetable gel for purification in mud drilling and reaming, gravel filling by jet suction with the gravel tank, well flushing by physical and chemical combination. Comparison of the water yield results before and after the technical measures proved that the technical measures have good effect on increasing the in-situ leaching water yield.