Well CGSD01 is a hydrothermal geothermal resource survey well organized and implemented by China Geological Survey. The well was completed at the depth of 405168m with diameter of 216mm. During the drilling process, problems such as insufficient safety factor for largediameter casing running, formation leakage, low core recovery in complex formation were encountered. This paper introduces the well structure as well as drilling and completion technology for the well. The complex problems in the drilling process were solved by taking some measures such as buoyancyaided casing setting, multiprocess leak plugging, improvement of the coring process in complex strata. The drilling technology and completion recommendations for the deep geothermal drilling in this area are summarized.