The performance of aluminum alloy drill rods is the bottleneck of the development of deep drilling technology. With the design of the drill string structure as the basis and in view of engineering requirements of ultra-deep hole drilling, the selection and evaluation of high strength and heat resistant aluminum alloy drill rod material were studied. The results showed that: the solution aging of 2219 aluminum alloy was 535℃/1h, 165℃/20 h, 2618 was 530℃/1h, 200℃/20h, respectively. The mechanical properties of 2219 aluminum alloy were better than 2618 aluminum alloy after long time heat exposure at ambient temperature and worse than 2618 aluminum alloy at transient high temperature. The element Zr in 2219 aluminum alloy can slow down the solute diffusion rate in the process of heat exposure, and it is beneficial to improve the residual strength after heat exposure.