With the Wangshan Village landslide as study subject, and with regard to the static anti-sliding stability in the project, indoor and field tests were conducted to analyze and evaluate the intrinsic factors affecting the stability of the Wangshan Village landslide, such as geological structures and site engineering conditions. The commercial software ABAQUS was used then to compute the model for slope reinforcement with anti-slide piles. The safety factors for the bottom pile, middle pile and top pile on the slope have been calculated and obtained. The calculation results show that the middle pile has the highest safety factor with 1.58. In view of the stress concentration at the foot of the slope under the static load and the acceleration amplification effect at the top of the slope under the dynamic load, the upper pile position and the lower pile position were designed around the middle of the slope, and the safety factors of two new positions were calculated. The results show that the safety factors of two positions are fairly high. Finally, comparison of the safety factors of five different pile positions on the slope has verified the feasibility of the upper pile and the lower pile, and the results can be taken as reference for the engineering works.