In order to better serve deep drilling engineering and accurately understand the plugging performance of the drilling fluid， six film-forming plugging agents were optimized and evaluated by sand bed test， API static water loss test， rheological property test and temperature resistance test in different drilling fluid systems. The results showed that 2^# and 4^# film-forming plugging agents had the best plugging performance among the six film-forming plugging agents， and the optimal dosage of them in the basic drilling fluid was 2%.The drilling fluid added with 2^# and 4^# plugging agents at 100℃ had better temperature resistance. The bentonite content and the additive are two important factors affecting the plugging performance of the drilling fluid： the higher the bentonite content， the better the plugging performance of the drilling fluid， and the plugging performance of the drilling fluid can be improved by adding polymer and the filtrate reducer. Sand bed experiment is an important basis to evaluate the plugging performance of the drilling fluid.