In view of the complex formation of ZK2401 borehole in Tanjiachong mining area of Stannary in Lengshuijiang City, the drilling construction of every single borehole is carried out as a system engineering, and the controllable part is controlled reasonably and effectively, so as to be prepared to move and improve the rate of borehole formation. This paper summarizes the drilling construction methods from four aspects: preliminary investigation, drilling structure design and drilling equipment selection, drilling engineering design and actual construction situation, in order to ensure the smooth deep hole drilling of small diameter in complex strata of mining area, and the experience can be used as reference for peers.