Luyi Sag in the Southern North China Basin provides beneficial geological conditions for the formation and development of shale gas. The area belongs to the marine-continental transitional facies strata. The strata are complex and the structure is well developed； and there are many mudstone strata in Shanxi Formation and Shangshihezi Formation， which are prone to collapse and block falling during drilling. The designed depth of Well Luye-1 for shale gas survey in the region is 3506.5m. In view of the difficulties in drilling works， optimization of drilling equipment， bits and drilling fluid systems was conducted， and the technical measures such as mud wall protection， deep hole coring and anti-deviation were summarized. These measures have ensured the smooth implementation of drilling operations and form a set of shale gas deep well drilling technology methods suitable for marine and continental transitional strata in Luyi Sag of Southern North China Basin. It provides a useful reference for the next implementation of similar drilling engineering， as well as safe， high-quality and efficient development of shale gas.