Groundwater contamination in China has developed from point-like to band-like and surface-like contamination. Traditional remediation materials are roughly placed， difficult to diffuse in the water-bearing media， and there are problems such as stratification of groundwater， variable storage states， difficulty in controlling injection parameters， and easy cross-contamination of various layers of water. To address these problems， this paper proposes an in-situ injection process that integrates vertical/guided drilling， rotary injection， micro-pressure fracture diffusion and expansion seal， develops an integrated drilling-injection tool， summarises the transport of remediation materials and remediation mechanisms during injection， lays the foundation for the design of in-situ remediation systems for contaminated sites， and provides a reference for green and precise remediation.