The tight sand formation reservoir of the Xujiahe-2 Formation in Xinchang Structure, western Sichuan has failed to form large-scale commercial development for a long time due to the unbalance of cost of drilling and benefit of production. In view of this phenomenon, through the series of scientific studies on the key drilling processes based on the optimization of setting positions, the hole size, the hole trajectory optimization, the combined drilling of the drilling tool, the low cost of the rotating guide tool in this paper. The comprehensive application of this technology in the block has achieved the breakthrough of shortening the shortest drilling cycle from 231.1 days to 95.7 days, achieved good application results, and realized the benefit development of the block.